Treatment of Non-Hodgkin’s Lymphoma with Sodium Phenylbutyrate (Antineoplastons)

Mary’s Story: A Journey from Hopelessness to Healing

Mrs. Siegel’s life was turned upside down when she was diagnosed with stage 4 Non-Hodgkin’s Lymphoma. Specialists from renowned institutions like Stanford and Dana-Farber Cancer Institute examined her case, only to confirm that her type of cancer was considered incurable with conventional therapies. The news devastated Mrs. Siegel, her husband, and their close family circle.

“I had lymphoma throughout my body, including my bone marrow, along with a fast-growing tumor, about half the size of an orange, protruding from my neck.”

— Mary, Non-Hodgkin’s Lymphoma Survivor

The only hope offered was an experimental approach at Dana-Farber: an autologous bone marrow transplant, which would involve massive doses of radiation and chemotherapy. While this treatment posed extremely high risks, it was presented as her best chance at a possible remission. However, due to concerns for her long-term health, Mrs. Siegel chose to decline this procedure.

Mary and her husband were heartbroken upon hearing the diagnosis and the lack of viable treatment options.

A Ray of Hope

Determined to find another option, Mrs. Siegel began researching alternative therapies and discovered Dr. Burzynski’s clinic in Houston, where he offered antineoplaston treatment (sodium phenylbutyrate and similar compounds). 

Unlike the traditional options, this non-toxic therapy offered a new approach without the usual side effects. In November 1992, Mrs. Siegel began her treatment with 4PBA. 

  • The only offered experimental conventional treatment involved a bone marrow transplant, high-dose radiation, and chemotherapy, a risky approach to treating low-grade lymphomas.
  • Despite the risks, it was her only hope for a possible remission. However, due to health concerns, she chose to decline the procedure and instead opted for therapy with sodium phenylbutyrate and its analogues (antineoplastons).

Alternative Therapy

Remarkably, after weeks of treatment with sodium phenylbutyrate and its derivatives, her neck tumor disappeared. Follow-up CT scans every three months at follow-up visits showed her other tumors shrinking as well. Even more importantly, Mary was able to lead a completely normal life during this treatment.

  • Mary began sodium phenylbutyrate and its derivative therapy (antineoplastons) in November 1992 while battling widespread lymphoma and a large tumor in her neck.
  • Within months, her visible tumor disappeared, and subsequent scans showed further tumor reduction.
  • Throughout the treatment, Mary maintained a high quality of life, able to live normally despite her condition.

Exploring New Treatment Options Beyond Conventional Care

Mrs. Siegel’s journey is a powerful example of how alternative treatments can offer hope when conventional options fall short. Her story highlights the impact of thinking beyond standard therapies and the importance of having choices in the face of life-threatening illness. For Mrs. Siegel, the 4PBA treatment was the key to a second chance at life, and her gratitude endures to this day.

“After just three weeks of treatment, the tumor disappeared. Subsequent CT scans, conducted every three months at UCLA, revealed that my other tumors were also shrinking. Most importantly, the quality of my life during treatment remained high—I was able to lead a completely normal life.”

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